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Perforin and Fas Cytolytic Pathways Coordinately Shape the Selection and Diversity of CD8(+)-T-Cell Escape Variants of Influenza Virus
Antigenic variation is a viral strategy exploited to promote survival in the face of the host immune response and represents a major challenge for efficient vaccine development. Influenza viruses are pathogens with high transmissibility and mutation rates, enabling viral escape from immunity induced...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1143766/ https://ncbi.nlm.nih.gov/pubmed/15956596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8545-8559.2005 |
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