Enhanced Potency of Plasmid DNA Microparticle Human Immunodeficiency Virus Vaccines in Rhesus Macaques by Using a Priming-Boosting Regimen with Recombinant Proteins

DNA vaccines have been used widely in experimental primate models of human immunodeficiency virus (HIV), but their effectiveness has been limited. In this study, we evaluated three technologies for increasing the potency of DNA vaccines in rhesus macaques. These included DNA encoding Sindbis virus R...

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Detalhes bibliográficos
Main Authors: Otten, Gillis R., Schaefer, Mary, Doe, Barbara, Liu, Hong, Srivastava, Indresh, zur Megede, Jan, Kazzaz, Jina, Lian, Ying, Singh, Manmohan, Ugozzoli, Mildred, Montefiori, David, Lewis, Mark, Driver, David A., Dubensky, Thomas, Polo, John M., Donnelly, John, O'Hagan, Derek T., Barnett, Susan, Ulmer, Jeffrey B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143738/
https://ncbi.nlm.nih.gov/pubmed/15956564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8189-8200.2005
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