Effect of CD8(+) Lymphocyte Depletion on Virus Containment after Simian Immunodeficiency Virus SIVmac251 Challenge of Live Attenuated SIVmac239Δ3-Vaccinated Rhesus Macaques

Although live attenuated vaccines can provide potent protection against simian immunodeficiency virus (SIV) and simian-human immunodeficiency virus challenges, the specific immune responses that confer this protection have not been determined. To test whether cellular immune responses mediated by CD...

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Main Authors: Schmitz, Jörn E., Johnson, R. Paul, McClure, Harold M., Manson, Kelledy H., Wyand, Michael S., Kuroda, Marcelo J., Lifton, Michelle A., Khunkhun, Rajinder S., McEvers, Kimberly J., Gillis, Jacqueline, Piatak, Michael, Lifson, Jeffrey D., Grosschupff, Gudrun, Racz, Paul, Tenner-Racz, Klara, Rieber, E. Peter, Kuus-Reichel, Kristine, Gelman, Rebecca S., Letvin, Norman L., Montefiori, David C., Ruprecht, Ruth M., Desrosiers, Ronald C., Reimann, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143721/
https://ncbi.nlm.nih.gov/pubmed/15956558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8131-8141.2005
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