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Elevated Levels of Interleukin-8 in Serum Are Associated with Hepatitis C Virus Infection and Resistance to Interferon Therapy

Hepatitis C virus (HCV), a major cause of liver disease worldwide, is frequently resistant to the antiviral alpha interferon (IFN). We have recently found that the HCV NS5A protein induces expression of the proinflammatory chemokine IL-8 to partially inhibit the antiviral actions of IFN in vitro. To...

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Autori principali: Polyak, Stephen J., Khabar, Khalid S. A., Rezeiq, Mohammed, Gretch, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114338/
https://ncbi.nlm.nih.gov/pubmed/11390624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6209-6211.2001
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