Elevated Levels of Interleukin-8 in Serum Are Associated with Hepatitis C Virus Infection and Resistance to Interferon Therapy

Hepatitis C virus (HCV), a major cause of liver disease worldwide, is frequently resistant to the antiviral alpha interferon (IFN). We have recently found that the HCV NS5A protein induces expression of the proinflammatory chemokine IL-8 to partially inhibit the antiviral actions of IFN in vitro. To...

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Detalhes bibliográficos
Main Authors: Polyak, Stephen J., Khabar, Khalid S. A., Rezeiq, Mohammed, Gretch, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114338/
https://ncbi.nlm.nih.gov/pubmed/11390624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6209-6211.2001
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