Epstein-Barr Virus Immediate-Early Protein BRLF1 Induces the Lytic Form of Viral Replication through a Mechanism Involving Phosphatidylinositol-3 Kinase Activation

Expression of the Epstein-Barr virus (EBV) immediate-early (IE) protein BRLF1 induces the lytic form of viral replication in most EBV-positive cell lines. BRLF1 is a transcriptional activator that binds directly to a GC-rich motif present in some EBV lytic gene promoters. However, BRLF1 activates tr...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Darr, Catherine Dayle, Mauser, Amy, Kenney, Shannon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6135-6142.2001
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