The Epstein-Barr Virus Immediate-Early Protein BZLF1 Induces both a G(2) and a Mitotic Block

The Epstein-Barr virus immediate-early protein BZLF1 is a transcriptional activator that mediates the switch from latent to lytic infection. Here we demonstrate that BZLF1 induces both a G(2) block and a mitotic block in HeLa cells and inhibits chromosome condensation. While the G(2) block is associ...

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Detalhes bibliográficos
Main Authors: Mauser, Amy, Holley-Guthrie, Elizabeth, Simpson, Dennis, Kaufmann, William, Kenney, Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136482/
https://ncbi.nlm.nih.gov/pubmed/12208981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.10030-10037.2002
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