Rearrangement of the Genes of Vesicular Stomatitis Virus Eliminates Clinical Disease in the Natural Host: New Strategy for Vaccine Development

Gene expression among the nonsegmented negative-strand RNA viruses is controlled by distance from the single transcriptional promoter, so the phenotypes of these viruses can be systematically manipulated by gene rearrangement. We examined the potential of gene rearrangement as a means to develop liv...

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Pubblicato in:	J Virol
Autori principali:	Flanagan, E. Brian, Zamparo, Joann M., Ball, L. Andrew, Rodriguez, Luis L., Wertz, Gail W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6107-6114.2001
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