Rearrangement of the Genes of Vesicular Stomatitis Virus Eliminates Clinical Disease in the Natural Host: New Strategy for Vaccine Development

Gene expression among the nonsegmented negative-strand RNA viruses is controlled by distance from the single transcriptional promoter, so the phenotypes of these viruses can be systematically manipulated by gene rearrangement. We examined the potential of gene rearrangement as a means to develop liv...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Flanagan, E. Brian, Zamparo, Joann M., Ball, L. Andrew, Rodriguez, Luis L., Wertz, Gail W.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6107-6114.2001
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