Hepatitis C Virus Nonstructural 5A Protein Induces Interleukin-8, Leading to Partial Inhibition of the Interferon-Induced Antiviral Response

Hepatitis C virus (HCV), a major cause of liver disease worldwide, is frequently resistant to the antiviral alpha interferon (IFN). The HCV nonstructural 5A (NS5A) protein has been implicated in HCV antiviral resistance in many studies. NS5A antagonizes the IFN antiviral response in vitro, and one m...

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Detalhes bibliográficos
Main Authors: Polyak, Stephen J., Khabar, Khalid S. A., Paschal, Denise M., Ezelle, Heather J., Duverlie, Gilles, Barber, Glen N., Levy, David E., Mukaida, Naofumi, Gretch, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114325/
https://ncbi.nlm.nih.gov/pubmed/11390611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6095-6106.2001
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