The Adenovirus Type 5 E1B-55K Oncoprotein Actively Shuttles in Virus-Infected Cells, Whereas Transport of E4orf6 Is Mediated by a CRM1-Independent Mechanism

The E1B-55K and E4orf6 proteins of adenovirus type 5 are involved in viral mRNA export. Here we demonstrate that adenovirus infection does not inhibit the function of the E1B-55K nuclear export signal and that E1B-55K also shuttles in infected cells. Even during virus infection, E1B-55K was exported...

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Detalhes bibliográficos
Main Authors: Dosch, Tanja, Horn, Florian, Schneider, Grit, Krätzer, Friedrich, Dobner, Thomas, Hauber, Joachim, Stauber, Roland H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114281/
https://ncbi.nlm.nih.gov/pubmed/11356976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5677-5683.2001
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