JC Virus Regulatory Region Tandem Repeats in Plasma and Central Nervous System Isolates Correlate with Poor Clinical Outcome in Patients with Progressive Multifocal Leukoencephalopathy

JC virus (JCV), the causative agent of progressive multifocal leukoencephalopathy (PML), has a hypervariable regulatory region (JCV RR). A conserved archetype form is found in the urines of healthy and immunocompromised individuals, whereas forms with tandem repeats and deletions are found in the br...

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Bibliografiska uppgifter
Huvudupphovsmän: Pfister, Luz-Andrea, Letvin, Norman L., Koralnik, Igor J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC114280/
https://ncbi.nlm.nih.gov/pubmed/11356975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5672-5676.2001
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