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JC Virus Regulatory Region Tandem Repeats in Plasma and Central Nervous System Isolates Correlate with Poor Clinical Outcome in Patients with Progressive Multifocal Leukoencephalopathy

JC virus (JCV), the causative agent of progressive multifocal leukoencephalopathy (PML), has a hypervariable regulatory region (JCV RR). A conserved archetype form is found in the urines of healthy and immunocompromised individuals, whereas forms with tandem repeats and deletions are found in the br...

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Autori principali: Pfister, Luz-Andrea, Letvin, Norman L., Koralnik, Igor J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114280/
https://ncbi.nlm.nih.gov/pubmed/11356975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5672-5676.2001
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