Sustained Dysfunction of Antiviral CD8(+) T Lymphocytes after Infection with Hepatitis C Virus

Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses influences long-term outcome. However, little is known about the functional capacity of HCV-specific T-lymphocyt...

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Detalhes bibliográficos
Main Authors: Gruener, Norbert H., Lechner, Franziska, Jung, Maria-Christina, Diepolder, Helmut, Gerlach, Tilman, Lauer, Georg, Walker, Bruce, Sullivan, John, Phillips, Rodney, Pape, Gerd R., Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114267/
https://ncbi.nlm.nih.gov/pubmed/11356962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5550-5558.2001
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