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Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3

Myeloid leukemia factor 1 (MLF1) was first identified as the leukemic fusion protein NPM-MLF1 generated by the t(3;5)(q25.1;q34) chromosomal translocation. Although MLF1 expresses normally in a variety of tissues including hematopoietic stem cells and the overexpression of MLF1 correlates with malig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yoneda-Kato, Noriko, Tomoda, Kiichiro, Umehara, Mari, Arata, Yukinobu, Kato, Jun-ya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142586/
https://ncbi.nlm.nih.gov/pubmed/15861129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600656
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