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Structural basis for recruitment of RILP by small GTPase Rab7
Rab7 regulates vesicle traffic from early to late endosomes, and from late endosomes to lysosomes. The crystal structure of Rab7-GTP in complex with the Rab7 binding domain of RILP reveals that Rab7 interacts with RILP specifically via two distinct areas, with the first one involving the switch and...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142575/ https://ncbi.nlm.nih.gov/pubmed/15933719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600643 |
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