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Structural basis for recruitment of RILP by small GTPase Rab7

Rab7 regulates vesicle traffic from early to late endosomes, and from late endosomes to lysosomes. The crystal structure of Rab7-GTP in complex with the Rab7 binding domain of RILP reveals that Rab7 interacts with RILP specifically via two distinct areas, with the first one involving the switch and...

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Autori principali: Wu, Mousheng, Wang, Tuanlao, Loh, Eva, Hong, Wanjin, Song, Haiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142575/
https://ncbi.nlm.nih.gov/pubmed/15933719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600643
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