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Structural basis for recruitment of RILP by small GTPase Rab7

Rab7 regulates vesicle traffic from early to late endosomes, and from late endosomes to lysosomes. The crystal structure of Rab7-GTP in complex with the Rab7 binding domain of RILP reveals that Rab7 interacts with RILP specifically via two distinct areas, with the first one involving the switch and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Mousheng, Wang, Tuanlao, Loh, Eva, Hong, Wanjin, Song, Haiwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142575/
https://ncbi.nlm.nih.gov/pubmed/15933719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600643
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