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Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation
Neural Wiskott–Aldrich syndrome protein (N-WASP) regulates reorganization of the actin cytoskeleton through activation of the Arp2/3 complex. Here, we show that heat shock protein 90 (HSP90) regulates N-WASP-induced actin polymerization in cooperation with phosphorylation of N-WASP. HSP90 binds dire...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142563/ https://ncbi.nlm.nih.gov/pubmed/15791211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600586 |
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