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Degradation of Hof1 by SCF(Grr1) is important for actomyosin contraction during cytokinesis in yeast

SCF-type (SCF: Skp1–Cullin–F-box protein complex) E3 ligases regulate ubiquitin-dependent degradation of many cell cycle regulators, mainly at the G1/S transition. Here, we show that SCF(Grr1) functions during cytokinesis by degrading the PCH protein Hof1. While Hof1 is required early in mitosis to...

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Dettagli Bibliografici
Autori principali: Blondel, Marc, Bach, Stéphane, Bamps, Sophie, Dobbelaere, Jeroen, Wiget, Philippe, Longaretti, Céline, Barral, Yves, Meijer, Laurent, Peter, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142548/
https://ncbi.nlm.nih.gov/pubmed/15775961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600627
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