The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane domain (7TM) cell-surface receptors. In 1996, we and others identified a superfamily of “regulator of G-protein signaling” (RGS...

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Bibliografiske detaljer
Main Authors: Siderovski, David P., Willard, Francis S.
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2005
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142213/
https://ncbi.nlm.nih.gov/pubmed/15951850
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