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Oral tolerance in the absence of naturally occurring Tregs

Mucosal tolerance prevents pathological reactions against environmental and food antigens, and its failure results in exacerbated inflammation typical of allergies and asthma. One of the proposed mechanisms of oral tolerance is the induction of Tregs. Using a mouse model of hyper-IgE and asthma, we...

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Autori principali: Mucida, Daniel, Kutchukhidze, Nino, Erazo, Agustin, Russo, Momtchilo, Lafaille, Juan J., Curotto de Lafaille, Maria A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142115/
https://ncbi.nlm.nih.gov/pubmed/15937545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24487
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