Recombinant Human Parvovirus B19 Vectors: Erythrocyte P Antigen Is Necessary but Not Sufficient for Successful Transduction of Human Hematopoietic Cells

The blood group P antigen, known to be abundantly expressed on erythroid cells, has been reported to be the cellular receptor for parvovirus B19. We have described the development of recombinant parvovirus B19 vectors with which high-efficiency, erythroid lineage-restricted transduction can be achie...

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Detalles Bibliográficos
Autores principales: Weigel-Kelley, Kirsten A., Yoder, Mervin C., Srivastava, Arun
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Gene Therapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114156/
https://ncbi.nlm.nih.gov/pubmed/11287560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4110-4116.2001
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