Construction and In Vitro Properties of a Series of Attenuated Simian Immunodeficiency Viruses with All Accessory Genes Deleted

We have generated simplified simian immunodeficiency virus (SIV) constructs lacking the nef, vpr, vpx, vif, tat, and rev genes (Δ6 viruses). To accomplish this, we began with an infectious molecular clone of SIV, i.e. SIVmac239, and replaced the deleted segments with three alternate elements: (i) a...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Guan, Yongjun, Whitney, James B., Detorio, Mervi, Wainberg, Mark A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Replication
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.9.4056-4067.2001
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!