Single Amino Acid Substitution in the V Protein of Simian Virus 5 Differentiates Its Ability To Block Interferon Signaling in Human and Murine Cells

Previous work has demonstrated that the V protein of simian virus 5 (SV5) targets STAT1 for proteasome-mediated degradation (thereby blocking interferon [IFN] signaling) in human but not in murine cells. In murine BF cells, SV5 establishes a low-grade persistent infection in which the virus fluxes b...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Young, D. F., Chatziandreou, N., He, B., Goodbourn, S., Lamb, R. A., Randall, R. E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3363-3370.2001
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