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Human Cytomegalovirus with IE-2 (UL122) Deleted Fails To Express Early Lytic Genes

Much evidence suggests that the major immediate-early (IE) transactivator of human cytomegalovirus (HCMV), IE-2, is likely to be critical for efficient viral replication; however, the lack of an IE-2 mutant HCMV has precluded an experimental test of this hypothesis. As an initial step toward charact...

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Autors principals: Marchini, Andrew, Liu, Haiqing, Zhu, Hua
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114097/
https://ncbi.nlm.nih.gov/pubmed/11160686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1870-1878.2001
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