Human Cytomegalovirus with IE-2 (UL122) Deleted Fails To Express Early Lytic Genes

Much evidence suggests that the major immediate-early (IE) transactivator of human cytomegalovirus (HCMV), IE-2, is likely to be critical for efficient viral replication; however, the lack of an IE-2 mutant HCMV has precluded an experimental test of this hypothesis. As an initial step toward charact...

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Pubblicato in:	J Virol
Autori principali:	Marchini, Andrew, Liu, Haiqing, Zhu, Hua
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.4.1870-1878.2001
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