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Conditional Transgenic System for Mouse Aurora A Kinase: Degradation by the Ubiquitin Proteasome Pathway Controls the Level of the Transgenic Protein

Aurora A is a mitotic kinase that localizes to centrosomes. Expression of this protein is normally limited to the mitotic stage (G(2)-M) of the cell cycle, whereas human cancer cells frequently exhibit overexpression of Aurora A protein regardless of the cell cycle stage. In the present study, Auror...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fukuda, Tomokazu, Mishina, Yuji, Walker, Michael P., DiAugustine, Richard P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140609/
https://ncbi.nlm.nih.gov/pubmed/15923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5270-5281.2005
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