Connexin 40, a Target of Transcription Factor Tbx5, Patterns Wrist, Digits, and Sternum

Haploinsufficiency of T-box transcription factor 5 (TBX5) causes human Holt-Oram syndrome (HOS), a developmental disorder characterized by skeletal and heart malformations. Mice carrying a Tbx5 null allele (Tbx5(+/Δ)) have malformations in digits, wrists, and sternum joints, regions where Tbx5 is ex...

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Detalhes bibliográficos
Main Authors: Pizard, Anne, Burgon, Patrick G., Paul, David L., Bruneau, Benoit G., Seidman, Christine E., Seidman, J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140596/
https://ncbi.nlm.nih.gov/pubmed/15923624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5073-5083.2005
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