MafA Is a Key Regulator of Glucose-Stimulated Insulin Secretion

MafA is a transcription factor that binds to the promoter in the insulin gene and has been postulated to regulate insulin transcription in response to serum glucose levels, but there is no current in vivo evidence to support this hypothesis. To analyze the role of MafA in insulin transcription and g...

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Autores principales: Zhang, Chuan, Moriguchi, Takashi, Kajihara, Miwako, Esaki, Ritsuko, Harada, Ayako, Shimohata, Homare, Oishi, Hisashi, Hamada, Michito, Morito, Naoki, Hasegawa, Kazuteru, Kudo, Takashi, Engel, James Douglas, Yamamoto, Masayuki, Takahashi, Satoru
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140590/
https://ncbi.nlm.nih.gov/pubmed/15923615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.4969-4976.2005
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