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Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

As an initial approach to studying the molecular replication mechanisms of hepatitis C virus (HCV), a major causative agent of acute and chronic liver disease, we have recently developed selectable self-replicating RNAs. These replicons lacked the region encoding the structural proteins and instead...

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Publicado no:J Virol
Principais autores: Lohmann, Volker, Körner, Frank, Dobierzewska, Aneta, Bartenschlager, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11152517/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.3.1437-1449.2001
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