Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

As an initial approach to studying the molecular replication mechanisms of hepatitis C virus (HCV), a major causative agent of acute and chronic liver disease, we have recently developed selectable self-replicating RNAs. These replicons lacked the region encoding the structural proteins and instead...

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Bibliografiske detaljer
Main Authors: Lohmann, Volker, Körner, Frank, Dobierzewska, Aneta, Bartenschlager, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114050/
https://ncbi.nlm.nih.gov/pubmed/11152517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1437-1449.2001
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