Identification of Three Functions of the Adenovirus E4orf6 Protein That Mediate p53 Degradation by the E4orf6-E1B55K Complex

Complexes containing adenovirus E4orf6 and E1B55K proteins play critical roles in productive infection. Both proteins interact directly with the cellular tumor suppressor p53, and in combination they promote its rapid degradation. To examine the mechanism of this process, degradation of exogenously...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Querido, Emmanuelle, Morisson, Megan R., Chu-Pham-Dang, Huan, Thirlwell, Sarah W.-L., Boivin, Dominique, Branton, Philip E.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.2.699-709.2001
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