The tumour suppressor protein p53 can repress transcription of cyclin B

The tumour suppressor protein p53 has functions in controlling the G(1)/S and G(2)/M transitions. Central regulators for progression from G(2) to mitosis are B-type cyclins complexed with cdc2 kinase. In mammals two cyclin B proteins are found, cyclin B1 and B2. We show that upon treatment of HepG2...

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Hauptverfasser: Krause, Karen, Wasner, Mark, Reinhard, Wibke, Haugwitz, Ulrike, Lange-zu Dohna, Christine, Mössner, Joachim, Engeland, Kurt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC113869/
https://ncbi.nlm.nih.gov/pubmed/11071927
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