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Transfection of insulin-producing cells with a transforming c-Ha-ras oncogene stimulates phospholipase C activity.

Pancreatic islet beta-cells and insulin-producing RINm5F cells were electroporated in the presence of the c-Ha-ras oncogene, to assess the possible involvement of the encoded product in coupling extracellular receptors to phospholipase C. After two days the c-Ha-ras-transfected cells increased their...

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Bibliographic Details
Main Authors: Berggren, P O, Hallberg, A, Welsh, N, Arkahammar, P, Nilsson, T, Welsh, M
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138575/
https://ncbi.nlm.nih.gov/pubmed/2658977
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