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Antisense-fos RNA causes partial reversion of the transformed phenotypes induced by the c-Ha-ras oncogene.

Several lines of evidence have suggested that c-fos may act downstream from c-Ha-ras in a growth-regulatory signal transduction pathway. We used antisense RNA to inhibit c-fos gene expression and investigated the effects of diminished c-fos expression on the phenotypes induced by the EJ c-Ha-ras onc...

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Publicat a:Mol Cell Biol
Autors principals: Ledwith, B J, Manam, S, Kraynak, A R, Nichols, W W, Bradley, M O
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1990
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1690847/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1545-1555.1990
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