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Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments

Major histocompatibility complex class II (MHC-II) molecules are composed of two polymorphic chains, α and β, which assemble with an invariant chain, Ii, in the endoplasmic reticulum. The assembled MHC-II complexes are transported to the Golgi complex and then to late endosomes/lysosomes, where Ii i...

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Detalhes bibliográficos
Main Authors: McCormick, Peter J., Martina, José A., Bonifacino, Juan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138261/
https://ncbi.nlm.nih.gov/pubmed/15911768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502206102
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