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The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner.

R-ras is a member of the ras family of small GTPases that associates with the apoptosis-suppressing proto-oncogene product Bcl-2. Using the yeast two-hybrid system we provide evidence for an interaction between R-ras and the Raf-1 kinase. This interaction requires only the N-terminal regulatory doma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Spaargaren, M, Martin, G A, McCormick, F, Fernandez-Sarabia, M J, Bischoff, J R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138162/
https://ncbi.nlm.nih.gov/pubmed/8002932
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