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Structural requirements for the utilization of ascorbate analogues in the prolyl 4-hydroxylase reaction.

The ability of structural analogues of ascorbate to serve as substitutes for this reducing agent in the prolyl 4-hydroxylase reaction was studied. In experiments using the purified enzyme, variations of the compounds' side chain were compatible with co-substrate activity. The presence of very l...

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Main Authors: Tschank, G, Sanders, J, Baringhaus, K H, Dallacker, F, Kivirikko, K I, Günzler, V
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138125/
https://ncbi.nlm.nih.gov/pubmed/8198555
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