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Feedback repression of polyamine transport is mediated by antizyme in mammalian tissue-culture cells.

Antizyme, a spermidine-induced protein that binds and stimulates ornithine decarboxylase degradation, is now shown also to mediate the rapid feedback inhibition of polyamine uptake into mammalian cells. Using a cell line (HZ7) transfected with truncated antizyme cDNA, and mutant ornithine decarboxyl...

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Detalles Bibliográficos
Main Authors: Mitchell, J L, Judd, G G, Bareyal-Leyser, A, Ling, S Y
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138014/
https://ncbi.nlm.nih.gov/pubmed/8166639
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