Periplasmic expression of human interferon-alpha 2c in Escherichia coli results in a correctly folded molecule.

Human interferon-alpha 2c (IFN-alpha 2c) was produced in Escherichia coli under the control of the alkaline phosphatase promoter using a periplasmic expression system. Compared with other leader sequences, the heat-stable enterotoxin II leader of E. coli (STII) resulted in the highest rate of correc...

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Bibliografische gegevens
Hoofdauteurs: Voss, T, Falkner, E, Ahorn, H, Krystek, E, Maurer-Fogy, I, Bodo, G, Hauptmann, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137919/
https://ncbi.nlm.nih.gov/pubmed/8141788
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