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Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coli()
BACKGROUND: Animal neurotoxin peptides are valuable probes for investigating ion channel structure/function relationships and represent lead compounds for novel therapeutics and insecticides. However, misfolding and aggregation are common outcomes when toxins containing multiple disulfides are expre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Pub. Co
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898981/ https://ncbi.nlm.nih.gov/pubmed/23999087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.08.021 |
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