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Inhibition of immediate-early-gene induction in renal mesangial cells by depletion of intracellular polyamines.

Mitogens have been shown to stimulate the activity of the rate-limiting enzyme for polyamine synthesis, ornithine decarboxylase (ODC), and ODC mRNA expression in cultured rat mesangial cells (MCs). In addition, inhibition of ODC by alpha-difluoromethylornithine (DFMO) results in growth arrest of MCs...

詳細記述

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書誌詳細
主要な著者: Schulze-Lohoff, E, Fees, H, Zanner, S, Brand, K, Sterzel, R B
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137909/
https://ncbi.nlm.nih.gov/pubmed/8141779
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