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Depletion of intracellular polyamines relieves inward rectification of potassium channels.

Two different approaches were used to examine the in vivo role of polyamines in causing inward rectification of potassium channels. In two-microelectrode voltage-clamp experiments, 24-hr incubation of Xenopus oocytes injected with 50 nl of difluoromethylornithine (5 mM) and methylglyoxal bis(guanylh...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Shyng, S L, Sha, Q, Ferrigni, T, Lopatin, A N, Nichols, C G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876254/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.12014
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