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Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum.

In order to determine whether the endoplasmic reticulum (ER) luminal FK506-binding protein, FKBP13, shares properties of ER molecular chaperones, MDCK cells were treated with either tunicamycin or Ca2+ ionophores. By Northern-blot analysis, tunicamycin resulted in a 2-fold rise in FKBP13 mRNA, where...

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Autors principals: Bush, K T, Hendrickson, B A, Nigam, S K
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137603/
https://ncbi.nlm.nih.gov/pubmed/7526846
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