Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi.

Sera of patients with chronic Chagas' disease (American trypanosomiasis) contain elevated levels of anti-alpha-galactosyl antibodies that are lytic to Trypanosoma cruzi. The T. cruzi trypomastigote F2/3 antigen complex recognized by these antibodies runs as a broad smear on SDS/PAGE [Almeida, K...

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Detalhes bibliográficos
Main Authors: Almeida, I C, Ferguson, M A, Schenkman, S, Travassos, L R
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137404/
https://ncbi.nlm.nih.gov/pubmed/7818483
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