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Accelerated degradation of 160 kDa epidermal growth factor (EGF) receptor precursor by the tyrosine kinase inhibitor herbimycin A in the endoplasmic reticulum of A431 human epidermoid carcinoma cells.
The effect of herbimycin A on the biosynthesis of epidermal growth factor (EGF) receptor was examined in human epidermoid carcinoma A431 cells. Cells were pulse-labelled with [35S]methionine, and EGF receptor biosynthesis was quantified by immunoprecipitation using a monoclonal anti-(EGF receptor) a...
Shranjeno v:
Main Authors: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1994
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1137143/ https://ncbi.nlm.nih.gov/pubmed/8037692 |
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