Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells.

The time course of Ca2+ and GTP-analogue effects on insulin secretion was investigated in HIT-T15 cells permeabilized with Staphylococcus alpha-toxin. These cells responded to Ca2+ in the range 0.1-10 microM and could be used in a dynamic perifusion system because of the minimal run-down of the secr...

Full description

Saved in:
Bibliographic Details
Main Authors: Jonas, J C, Li, G, Palmer, M, Weller, U, Wollheim, C B
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137112/
https://ncbi.nlm.nih.gov/pubmed/8042998
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items