Tokaracetin, a new platelet antagonist that binds to platelet glycoprotein ib and inhibits von Willebrand factor-dependent shear-induced platelet aggregation.

A new platelet antagonist, tokaracetin, was isolated from the venom of Trimeresurus tokarensis by ion-exchange chromatography, heparin-Sepharose chromatography and hydrophobic HPLC. The purified protein showed an apparent molecular mass on SDS/PAGE of 28.9 kDa under non-reducing conditions. On reduc...

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Hauptverfasser: Kawasaki, T, Taniuchi, Y, Hisamichi, N, Fujimura, Y, Suzuki, M, Titani, K, Sakai, Y, Kaku, S, Satoh, N, Takenaka, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136815/
https://ncbi.nlm.nih.gov/pubmed/8948455
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