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Heat shock of human synovial and dermal fibroblasts induces delayed up-regulation of collagenase-gene expression.

We investigated the effect of heat shock on the expression of the collagenase gene in normal human synovial and dermal fibroblasts. Heat shock (42-44 degrees C for 1 h) caused a marked increase in heat-shock protein 70 (HSP-70) mRNA levels, followed by a delayed increase in collagenase mRNA levels,...

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Main Authors: Hitraya, E G, Varga, J, Jimenez, S A
格式: Artigo
語言:Inglês
出版: 1995
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136787/
https://ncbi.nlm.nih.gov/pubmed/8948427
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