Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide.

We have developed a novel method for monitoring the mitochondrial permeability transition in single intact hepatocytes during injury with t-butylhydroperoxide (t-BuOOH). Cultured hepatocytes were loaded with the fluorescence probes, calcein and tetramethylrhodamine methyl ester (TMRM). Depending on...

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Bibliografische gegevens
Hoofdauteurs: Nieminen, A L, Saylor, A K, Tesfai, S A, Herman, B, Lemasters, J J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136750/
https://ncbi.nlm.nih.gov/pubmed/7718000
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